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The Effects of GLP-1 Agonists on Musculoskeletal Health and Orthopedic Care

Wegovy (Semaglutide) and Zepbound (Tirzepatide) are FDA-approved, once-weekly injectables designed for adults with obesity or those who are overweight with weight-related health conditions

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Genetic predispositions in peptide pathways support clinical context but do not predict exact medication response
Pituitary adenylyl cyclase-activating protein induces the voltage-independent activation of inward membrane currents and elevation of intracellular calcium in HIT-T15 insulinoma cells