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Not everyone gets nausea, but its one of the most reported early side effects

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite

It is known through scientific studies to inhibit an important enzyme in the metabolism of many medications, known as cytochrome P450 3A4 or CYP3A4

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