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Author Contributions Concept and design: Kristina Nazzicone, Ashley O'Toole Acquisition, analysis, or interpretation of data: Kristina Nazzicone, Ashley O'Toole, Michael Sidiropoulos Drafting of the manuscript: Kristina Nazzicone Critical review of the manuscript for important intellectual content: Ashley O'Toole, Michael Sidiropoulos Supervision: Ashley O'Toole References 1.Population-based prevalence and incidence estimates of primary discoid lupus erythematosus from the Manhattan Lupus Surveillance Program

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The patches are covered in microneedles that painlessly penetrate the skin and thus enable pushing the active ingredients into the dermis