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Sterility testing following USP protocols confirms absence of bacterial and fungal contamination, critical for injectable formulation development

NDA 215866) and chronic weight management in adults with obesity or overweight (brand name: Zepbound, FDA approval November 2023

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Evidence Balance Note Peer-reviewed clinical literature supports GLP-1 medications for weight management in appropriate candidates, while also documenting meaningful side effect profiles, contraindications, and weight regain following discontinuation

The GLP-1 market will bifurcate into a branded premium injectable tier for highest-efficacy patients and an oral generic access tier for cost-sensitive patients growing total prescription volumes while compressing per-unit average selling prices from 2030 onward