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Techniques like ion-pairing reversed-phase liquid chromatography (IP-RPLC) are widely used to monitor peptide critical quality attributes (CQAs), with hyphenated LC-MS approaches playing a key role in enhancing sensitivity and selectivity, enabling quantification of low-level impurities

Liraglutide then became available, and several other GLP-1 analogs are in development

Stopping any of these medications abruptly can lead to rebound hunger, blood sugar fluctuations, and weight regain

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have transformed the therapeutic landscape of type 2 diabetes (T2D) and obesity by offering substantial weight loss and cardiometabolic protection