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The vascular hypometabolism hypothesis reframes dementia as a disorder of energy delivery, where chronic reductions in cerebral blood flow and glucose utilization precede and likely contribute to amyloid and tau pathology

doi:10.1111/dom.12591 Suran M

Ensuring adequate maternal nutrition is crucial to support both milk production and the nutrient content of breast milk, which could otherwise be compromised

"The progression of elecoglipron is an important step in delivering a differentiated weight management portfolio, offering monotherapies and combinations, designed to address the biological complexity of obesity and comorbidities that can be tailored to individual needs, enabling people to live healthier lives." Sharon Barr, Executive Vice President, BioPharmaceuticals R&D, AstraZeneca Weight Loss Results In AstraZeneca's VISTA Phase 2b trial , adults living with obesity or overweight plus at least one weight-related condition lost an average of 10.5% of their body weight after 26 weeks on the highest dose of elecoglipron