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Results demonstrated that RETA and SEMA induced an immediate but transient reduction in food intake that rebounded after 2 weeks of treatment to control levels of intake quantified in the Veh group (Supplementary Fig

For example: People put on GLP-1 drugs might differ in meaningful ways from those started on SGLT-2s or DPP-4s Severity of diabetes, weight, blood pressure patterns, sleep apnea, smoking history, and other factors can be hard to capture perfectly in claims Diagnostic coding can be imperfect Follow up time was up to 18 months, not years That said, the study is large, and it tries to do the comparison thoughtfully

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If youre using GLP-1 for weight loss or managing type 2 diabetes, you may be wondering: Does it also help with cholesterol? The short answer: yes there is good evidence that GLP-1 can modestly improve cholesterol and overall lipid profiles in some patients

But their heart benefits likely come from a combination of effects