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The first interchangeable biosimilar insulin: Insulin glargine-yfgn, Journal of Diabetes Science and Technology (2021) Post-marketing safety of Lantus and its interchangeable biosimilar Semglee in the United States: A disproportionality analysis using the FDA Adverse Event Reporting System (FAERS) database, Diabetes, Obesity, and Metabolism (2025) Highlights of prescribing information, SEMGLEE (insulin glargine-yfgn) injection, for subcutaneous use, Food and Drug Administration (2023) Highlights of prescribing information, LANTUS (insulin glargine) injection, for subcutaneous use, Food and Drug Administration (2023) Biosimilars: What patients with diabetes need to know, Food and Drug Administration Efficacy and safety of MYL-1501D versus insulin glargine in people with type 1 diabetes mellitus: Results of the INSTRIDE 3 phase 3 switch study, Diabetes, Obesity, and Metabolism (2019) Insulin cost and affordability, American Diabetes Association (2025) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

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Serious liver harm from semaglutide is not a recognized safety concern, and the medication is specifically recommended for patients with metabolic liver disease due to its protective effects

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\Metabolic Flexibility: Enhanced lipid oxidation and ketone production support cardiometabolic health