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Patients often want to get to the effective dose quickly, but rushing can make side effects harder than they need to be

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A meta-analysis evaluated seven cardiovascular studies of GLP-1 RAs, stating that GLP-1 RAs treatment can reduce broad composite kidney outcomes, including the sustained decline in eGFR, emergence of new macroalbuminuria, progression to end-stage kidney disease (ESKD), or death from renal causes [154]
95% CI, 0.37 to 4.78

Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met + SU): A randomised controlled trial