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Given that finerenone was beneficial in patients already receiving an SGLT2 inhibitor, our findings point to finerenone as a new second pillar in HFmrEF/HFpEF. Approved in 2021 based on data from the FIDELIO-DKD and FIGARO-DKD trials, Bayer announced on August 05, 2024 the FINEARTS-HF trial had met its primary endpoint

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Immunocytochemistry for detection of GLP-1 Cultures of mouse intestinal cells were fixed for 10 min at room temperature in PBS containing 4% paraformaldehyde, and were then permeabilized by incubation for 10 min in PBS containing 0.25% Triton X-100

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