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Seizures are not listed among known adverse effects in the Summary of Product Characteristics or MHRA guidance

A majority of the digestive side effects of semaglutide tend to be most frequent and intense at the beginning of treatment or during dose escalation

Plant proteins, on the other hand, are not associated with these health problems

J Am Coll Cardiol 2014;63(25 B):29352959

This suggests heterogeneity in cardiorenal benefit based on cardiovascular phenotype in SGLT2is, and is an important factor with future research regarding semaglutides potential differential effects across CKD populations with or without overt HF[62]