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Description
Quick Answer: Semaglutide is a proven, FDA-approved GLP-1 medication for weight management

Lai TW, Zhang S, Wang YT

The first significant factor identified was the duodenal glucose-dependent insulinotropic polypeptide, GIP, which however, turned out not to stimulate insulin secretion in patients with type 2 diabetes

Health Canadas review of the safety data concluded that the safety profile of semaglutide tablets, including the frequency of GI AEs, was comparable to the other previously authorized GLP-1 RAs, including semaglutide injection

Other GLP-1 issues Less common complications that resulted in hospital visits included allergic reactions, pancreatitis, and bile duct disease
