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doi: 10.3390/ijms22062834

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By activating both GIP and GLP-1 receptors, Mounjaro enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetiteall of which contribute to improved glycaemic control and weight loss

A 2025 case series discussed in the episode found athletes who combined GLP-1 medications with resistance training three to five times per week and prioritised protein intake were able to preserve or even increase lean tissue while losing fat mass