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Obesity is the strongest modifiable risk factor for OSA
376,380 The therapeutic effects of PF1801 are primarily achieved by modulating several key proteins that play central roles in inflammation and cellular metabolism
Weeks 1-2 represent the adjustment period
Metformin is also associated with reversible gastrointestinal side effects that include diarrhea, nausea, flatulence, dyspepsia, vomiting, and abdominal pain
