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Description
Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium
Same pattern
Rather than reproducing the peptides sprawling footprint, the small molecule tucks into a compact, mostly hydrophobic pocket in the upper portion of the helical bundle
This helps preserve vital skeletal muscle and maintains a healthy metabolic rate
doi: 10.1016/j.anai.2022.08.735
