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On August 15, 2025, the FDA granted accelerated approval to Wegovy (semaglutide 2.4 mg) for treating adults with non-cirrhotic MASH and moderate to advanced liver fibrosis

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Those with no active infections or bleeding disorders are suitable since the treatment involves blood extraction and injections

There is no ready explanation for the divergent data, and it is not known whether ghrelin has the same effect in L-cells in vivo

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