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Weight Maintenance After Injectable# Recommendation : Orforglipron Reason : ATTAIN-MAINTAIN demonstrated that patients switching from injectable tirzepatide or semaglutide to orforglipron maintained their weight loss, validating oral step-down therapy

Start Low and Go Slow: Always follow your prescribers dosing instructions exactly

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We start with the patient: weight history, prior attempts, family history, blood pressure, glucose, cholesterol, liver markers, sleep, medications, mental health, alcohol use, menopause or PCOS context when relevant, and what the patient is actually trying to accomplish