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The metabolic adaptation that follows weight loss, combined with a lower lean mass, makes weight easier to regain if the medication is stopped or eating drifts back up

( 10.1016/j.molmet.2020.101090) [DOI] [PMC free article] [PubMed] [Google Scholar] Baggio LL, Ussher JR, McLean BA, Cao X, Kabir MG, Mulvihill EE, Mighiu AS, Zhang H, Ludwig A, Seeley RJ, et al

A High Visceral-to-Skeletal Muscle Area Ratio on Cross-Sectional Imaging Is Associated with Failure of Standard Ustekinumab Doses: A Multicenter Study
