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Recent research indicates that drugs targeting incretin may help reduce inflammation and blood clotting in sepsis by activating the GLP-1 receptor 24

Future research should focus on biomarker-informed stratification, comparative trials with standard treatments, and integration of GLP-1 RAs into multimodal care frameworks

Third, mechanistic studies, both clinical and translational, which probe inflammatory signaling, insulin/IGF pathways, and the gut microenvironment to determine whether observed benefits are predominantly tumorintrinsic, hostsystemic, or both, said Cuomo

[DOI] [PMC free article] [PubMed] [Google Scholar] 496.Traussnigg, S

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