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Consult your doctor or a qualified dietitian before beginning any fitness programme or making changes to your diet or lifestyle.

For example, the SELECT trial reported that semaglutide reduced the risk of MACE by 20% (Hazard Ratio (HR) 0.80, 95% confidence interval (CI) 0.720.90) in people with obesity but without diabetes, although several secondary outcomes did not reach statistical significance under hierarchical testing procedures

Research-grade semaglutide from unregulated online suppliers carries significant risks including unverified purity, inaccurate dosing, no cold-chain guarantee and no medical supervision

For women with type 2 diabetes who were taking GLP-1 medications before pregnancy, discontinuation is recommended before conception or as soon as pregnancy is confirmed

Results can last up to a year or more, with optional maintenance treatments available every 6 to 12 months to extend the benefits
