glp 1 agonist indications The expanding benefits of GLP-1 medicines: Cell Reports Medicine Glucagon-like peptide-1 receptor: mechanisms and

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Since brain GLP-1R signaling is to a large extent directly triggered by its peripheral secretion from the intestines via vagal stimulation of the NTS neurons, it seems plausible that proper balance in gut microbiota abundance and diversity can influence action of this peptide in the central nervous system

Annahern J, Kruger DF, Gatcomb PM, Petit WA, Tamborlane WV (1989) The Diabetes Control and Complications Trial (DCCT): the trial coordinator perspective