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A 2023 cost analysis compared the two by looking at how much it costs to achieve a 1% reduction in body weight

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After a follow-up of 27 months, the researchers reported that just over half of patients (54%) discontinued their prescription for at least 135 days

Results have shown that stopping the medication may result in weight gain

Using high resolution manometry with topographic plotting, three major subtypes of EGJ pressure morphology are demonstrable (Figures 9 and 10): type I with the crural diaphragm completely superimposed on the LES, type II with 12 cm separation between the two, and type III with greater than 2 cm separation
