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Comparative treatment of Sulfasalazine+Ezetimibe combination and Sulfasalazine in a rat model with induced colitis

An increase in oxidative stress and ROS production play a role in mitochondrial DNA damage, respiratory impairment, and calcium imbalance, where all these symptoms of mitochondrial dysfunction are associated with AD

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37 Additionally, these agents reduce the levels of proinflammatory adipokines and the expression of inflammatory genes, which can improve overall metabolic health

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