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Primary endpoints Energy expenditure and RER under indirect calorimetry, fat mass and adipocyte size, liver triglyceride content and histology, plasma lipids, and muscle performance form a coherent endpoint suite tied to ERR biology

HbA1c, with levels 6.5% was not considered to be a marker of malnutrition, however

Studies suggest that approximately 90% of diabetic men experience varying degrees of testicular dysfunction, manifesting as testicular degeneration and increased abnormal sperm proportions in the epididymis [7, 30, 31]

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The types and amount of food consumed will be recorded by participants in household measures (e.g