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For those worried about eating before bed, a study on weight-lifting women found that drinking a casein-based protein shake didn't blunt overnight lipolysis (the breakdown of fats)

At the same time, it is essential to recognize the limits of the GLP-1 paradigm as a universal model

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Diagnostic Uses of C-Peptide in Diabetes C-peptide, a peptide produced in equal amounts with insulin, serves as a valuable diagnostic tool in diabetes management

nausea decreases with ongoing usage a steady weight loss occurs in some patients over 2 years (may be related to nausea & CNS-mediated loss of appetite) there is an increased risk of hypoglycemia when exenatide is used with a sulfonylurea The dose of the sulfonylurea may need to be reduced if hypoglycemia occurs when combined with exenatide Most serious : rare & sometimes fatal necrotizing or hemorrhagic pancreatitis When initiating patients on Byetta, watch for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back, which may or may not be accompanied by vomiting)
