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To investigate these possibilities, in this study we performed a detailed comparison of the prototypical GLP-1R therapeutic agonist exendin-4 with an equivalent peptide bearing a C16 fatty diacid at its C-terminus, focusing on the relative propensities of each ligand to engage with G protein and -arrestin recruitment and activation, endocytosis and post-endocytic sorting

Certain medical conditions or other health factors may raise the risk of interactions with Januvia

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