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There is also a separate safety question, distinct from efficacy: retatrutide raises resting heart rate by 5 to 10 beats per minute, which has not yet been characterised in patients who already have heart failure or irregular heartbeats

Ozempic generated about seven times more reports than Wegovy, owing to its earlier approval in 2017 vs

[15] However, subsequent analysis revealed important context: the increased risk was predominantly observed in patients with pre-existing diabetic retinopathy and those who experienced rapid improvements in glycaemic control

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