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N Engl J Med 387(3):205216 Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M et al (2015) A randomized, controlled trial of 3.0 mg of liraglutide in weight management

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Being studied for obesity, type 2 diabetes, obstructive sleep apnea, and hypertension in adults with obesity

The weight-loss effects are not comparable

Metformin activates AMPK via two primary pathways (25)