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Antidiabetic medications in patients with depression Because the bidirectional association between IR, T2DM and depression is an evolving research area, studies testing or supporting the beneficial effects of antidiabetic drugs on depression are increasing exponentially

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When should I call my prescriber about side effects

AAIC 2026 A comparative effectiveness analysis of second-line diabetes medications in realworld registry (Danish registry) comparing GLP-1 RAs to other agents found a protective effect of GLP-1 RAs vs certain other second-line drugs over 5 years, though not against all comparators

Although an increase in heart-rate per se is not a major problem for most people, it is salient in the case of GLP1R, GIPR or GR agonists since the target patient population of these agonist are obese patients, who likely already suffer from cardiovascular complications