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NICE guidelines (NG28) support their use in specific clinical scenarios, particularly for patients with a BMI 30 kg/m (or 27 kg/m in certain ethnic groups) when HbA1c targets are not met or when weight reduction would provide significant health benefits

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*Correspondence: Fenglei Zhang [email protected] Yan [email protected] Xu [email protected] This article was submitted to Heart Failure and Transplantation, a section of the journal Frontiers in Cardiovascular Medicine These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Below, we summarize the most recent guideline updates highlighting the evolving role of GLP-1 RAs in cardiometabolic care in Table 3
In 2023, it expanded into prescription weight-loss medications, adding GLP-1s to the mix while keeping its education-first foundation intact
