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Regulatory nods for Wegovy in Mexico and Brazil widen eligibility to millions of high-BMI adults, while cardiovascular-outcome data support use in secondary prevention
GIP(3-30)NH 2 demonstrated an inhibition of the GIP-potentiated glucose-stimulated insulin secretion by 82%
A study in rats (Ramrez et al., 2018) has showed that the DPP4 inhibitor sitagliptin induces a lowering of fatty acid utilization in cardiomyocytes in favour of glucose
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Pooled results from three RCTs ( 2 = 15%) ( Figure 2C )
