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The incretin hormone glucagonlike peptide 1 increases mitral cell excitability by decreasing conductance of a voltagedependent potassium channel

The available studies are limited to short-term results, and there are little data on the long-term safety or sustained weight loss after discontinuation of the medication, leading to concerns about possible weight regain [74]

prausnitzii may be one of the important pathways through which GLP-1 agonists work to regulate glucose in type 2 diabetes

Notably, GLP-1RAs benefit pain management through their neuroprotective and metabolic regulatory properties, such as inhibiting inflammation responses and oxidative stress, promoting -endorphin release and modulating several other crucial biological pathways