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The addition of glucagon receptor activation increases energy expenditure, which is why retatrutide shows higher weight loss numbers in early trials
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Tirzepatide (Mounjaro), the dual GIP/GLP-1 receptor agonist, is licensed by the MHRA for the treatment of type 2 diabetes
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Diabetes remission marker : 75% of patients on 36 mg achieved A1C 6.5%
