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Only 27.7% and 7.8% of the enrolled patients were women or aged 75 years or older, respectively [81]

[DOI] [PubMed] [Google Scholar] 5.Nakagami T., DECODA Study Group Hyperglycaemia and mortality from all causes and from cardiovascular disease in five populations of Asian origin
So while the medications can produce remission-like states, theyre managing the condition rather than permanently curing it

Beta-cell function improvements, if they occurred during treatment, can persist for months beyond cessation

Another report showed that sitagliptin (576 mg/kg) reduced plaque macrophage infiltration and matrix metallopeptidase-9 (MMP-9) levels in ApoE / mice [26] and increased activation of AMPK and AKT signaling pathway but inhibited MAPK and ERK1/2 signaling in aorta of ApoE / mice [66]
