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Plasma PYY levels are increased by insulin-like growth factor 1 (IGF-1), bombesin, and calcitonin-gene-related peptide and decreased by GLP-1
One recent epidemiologic study examined health records of over 500,000 people with OUD and found that those prescribed a GLP-1 receptor agonist had approximately half the rate of opioid overdoses compared to those without such prescriptions (Qeadan F et al, Addiction 2024;115)
by Regina Schaffer Disclosure s : Martin is vice president of Lilly Medical Affairs

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