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Additionally, as a strength, liver biopsies were centrally assessed by two independent and blinded pathologists

Contraindication: a specific history that makes the medication unsafe or inappropriate for a given person
Heisler LK, Kanarek RB, Gerstein A

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49)

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