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GLP-1 is secreted by intestinal L-cells in response to food intake and promotes insulin secretion from pancreatic -cells, thereby playing a key role in regulating the blood glucose concentration 20,21,22,23

The IAG Perspective: What This Means for Clinical Development Every dimension of this transformation the disease reclassification, the GLP-1 pipeline expansion, the indications stretching into aging, hypertension, liver disease, and neurodegeneration, converges on a single operational reality: the clinical trial programs required to support these drugs are extraordinarily complex imaging challenges

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Follow-up: Minimum follow-up duration of 6 months

Some potential users may not be able to tolerate the side effects or may simply not need or want to lose that much weight