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At the category level, mild localized skin redness or itching at the application site is the most commonly reported issue with adhesive patches of any kind - this typically comes from the adhesive material, not the botanical ingredients themselves

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This could explain why some people experience anxiety early in treatment that resolves as they continue

Adverse effects were more common at high doses of the medication (8 mg and 12 mg once weekly)

Side Effect Management: Should side effects occur, a medical professional can help manage them effectively, adjust dosages, or recommend alternative strategies to ensure your safety and comfort