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The venture-backed group has raised a combined $2.8 billion in funding, reflecting the intense investor appetite in the category

Studies have shown that bitter-tasting pharmaceuticals and substances, including polyphenols such as isosinensetin, bind to bitter taste receptors, and unlike other TAS2R agonists, stimulate GLP-1 secretion in NCI-H716 cells [192] (Fig
Gold SL, Rabinowitz LG, Manning L, Keefer L, Rivera-Carrero W, Stanley S, et al
As a GLP-1 receptor agonist, it mimics the action of a natural hormone in the body that helps regulate blood sugar, insulin secretion, and appetite
