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Barriers and Strategies for Oral Peptide and Protein Therapeutics Delivery: Update on Clinical Advances

Experimental Gerontology, 133, 110875

Thus, our data suggested that PFKFB3-driven glycolysis could facilitate NLRP3 inflammasome activation by supplying excessive production of lactate in TGF-1 + IL-1-activated fibroblasts

This sensitivity is why travel planning matters: a pen that's been frozen or overheated may look completely normal while delivering a fraction of its intended dose
