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Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach

100% of participants on the 8 mg and 12 mg doses in Phase 2 achieved at least 5% weight loss

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In the multicenter STEP trial with patients with overweight or obesity and heart failure with preserved ejection fraction (STEP-HFpEF), patients treated with semaglutide 2.4 mg had mean percentage reduction in body weight of 13.3% and experienced significant improvements in heart failure-related symptoms, walking distance, and blood pressure measurements from baseline to 52 weeks [15]