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Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

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A., Baggio, L

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Results for Study 3 At the end of the 12-week intensive lifestyle intervention lead-in, for patients who subsequently entered the randomized treatment period (n=579), the average body weight loss due to lifestyle was 6.9% (Week -12 to Week 0)

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Dit is op de korte termijn, op de lange termijn is het nog onbekend of patienten op gewicht blijven

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Tirzepatide binds the GLP-1 receptor with lower affinity than semaglutide and exhibits distinct signaling bias, which may result in comparatively different downstream GLP-1 receptor signaling dynamics 23

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