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Nevertheless, concerning case reports and retrospective studies have emerged in 2023 of undigested gastric contents in sedated/anaesthetised patients undergoing elective endoscopy with unprotected airways: Klein and Hobai (2023) published a case report of a patient taking semaglutide for weight loss who experienced pulmonary aspiration from undigested food content identified during routine gastroscopy, despite fasting 18hr prior to the procedure

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It addressed the short half-life issue by structural design and delivered strong outcomes, including the first evidence of major clinical benefits (like indications of improved cardiovascular risk factors)

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She told PA: "It was working so well for him I thought, 'oh, well, maybe I'll have a go'." Dame Prue admitted she disregarded the pharmacists' guidance regarding daily calorie intake, resulting in her body entering "starvation mode"