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Learn what happens week 1 to 4, how to manage early side effects, realistic weight loss numbers & nutrition strategies that work.

GLP-1-based therapies helped adults with overweight or obesity lose weight mainly by reducing fat mass and visceral adipose tissue, while lean body mass losses were generally modest

There can be side effects and risks: GLP-1 drugs affect multiple systems (pancreas, kidney, GI tract) and are not without cost or health implications

Semaglutide prescription for weight loss has expanded far beyond endocrinologists

Glucagon-like peptide-1 (GLP-1) is an incretin hormone mainly secreted from intestinal L cells in response to nutrient ingestion