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When added to metformin, the GLP-1 receptor agonists achieve a mean HbA1c reduction of 0.99%,28 together with a significant weight loss (expected 2.9kg on average).40 The GLP-1 receptor agonists do not induce hypoglycemia when administered in monotherapy
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Timing issues also cause denials when patients have recently tried other weight management approaches that the insurer considers insufficiently documented
The concern is what happens when manufacturers control the prescribing pathway directly
