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Rising obesity prevalence and expanding treatment guidelines favoring GLP-1 therapies are accelerating adoption
Also, SGLT-2is have been associated with a lower Firmicutes/Bacteroidetes ratio and a lower number of pathobionts such Enterobacteriaceae , which suggests that the body is moving toward a more eubiotic state [34]
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Similarly, improvements in adipose tissue insulin sensitivity enhance the ability of insulin to suppress lipolysis, thereby reducing the flux of free fatty acids to the liver
