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Up to now all the prospective GPR119 agonists were plagued by low bioavailability, lack of efficacy and more importantly, cardiotoxicity which has stopped all human studies before any large scale Phase III clinical trials (239)

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That's not something I ever thought I'd say. Diana M., 46 , 5'7" Start 344 lbs Current 238 lbs Lost 106 lbs I'd been heavy my whole adult life

By mimicking and enhancing this process, semaglutide has been clinically proven to help people lose weight

Further, the market is shifting toward oral and long-acting GLP-1 formulations, as patients prefer fewer injections and more convenient treatment options