glp-1 news 2025 october 16 Looming drug patent expirations draw generics firms Who Gets the Shot? GLP-1

For example, liraglutide, a GLP-1 receptor agonist, improved cognitive function in n = 19 patients with major depressive disorder (MDD) or bipolar disorder in a pilot randomised controlled trial (RCT) [16], whilst a systematic review and meta-analysis reported a pooled reduction in depressive symptoms with GLP-1 receptor agonists compared to other antidiabetic therapies [17]

Funding MB and KI are part funded by the NIHR Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and Kings College London

PlexusDx supports this progression through regular check-ins, dose titration guidance, and coordination with your endocrinologist to optimize both thyroid control and metabolic health

Clin J Am Soc Nephrol 2021;16:1345-54.PubMedPMC 110

semaglutide or tirzepatide), are of benefit following metabolic surgery