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The predominant bioactive fraction consists of chlorogenic acids, which account for 7176% of total polyphenols, together with methylxanthines, saponins and flavonoids (2, 3)
Nat Reviews Endocrinol
2 Tirzepatide (Mounjaro, Eli Lilly) is a dual GLP-1 and GIP receptor agonist medication that depends heavily on GIP agonism
In neurons, cAMP and PKA signaling pathways regulate synaptic plasticity by regulating pathways related to N-Methyl-D-aspartic acid (NMDA) and aminomethylphosphonic acid receptor signaling such as calcium influx into intracellular membranes to change synaptic plasticity for long-term potentiation related to memory function [42-45]
Chaves Filho AJM, Cunha NL, de Souza AG, Soares MV, Juc PM, de Queiroz T, et al
