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Beumer et al., 2018, 2020)
Cohort entry was defined as the date of the first-ever prescription for one of the drugs of interest (GLP-1RAs, SGLT2 inhibitors, metformin or other second- or third-line glucose-lowering drugs) during the study period, and their respective first exposure was defined as the index event
However, future research should investigate the potential of GLP-1RAs in autoimmune and fibrotic diseases, assess their combination with other anti-inflammatory agents to enhance synergistic effects, and conduct long-term, head-to-head trials to compare efficacy, safety, and tolerability across different GLP-1-based therapies
Lose enough muscle, and your metabolism drops significantly beyond what would happen from fat loss alone
She doesnt touch gluten, sugar or dairy